Episode 20 of "Grey's Anatomy"
s02e11 Owner of a Lonely Heart
Title: Owner of a Lonely Heart
Original Air Date: 12/04/2005 on ABC
Plot Outline:
Cristina Yang has little sympathy for Constance Ferguson (special guest star Rosanna Arquette), a prison inmate who jeopardizes her health just to get out of solitary confinement. Meanwhile the interns all keep careful watch on the family of premature quintuplets with a variety of serious health challenges, Izzie's anger at Alex reaches boiling point, and Dr. Addison Shepherd decides to teach Izzie a very painful lesson.